| Define Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and explain the rationale for the recent change in nomenclature. |
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| Describe the primary health risks associated with MASLD, including its impact on cardiovascular health, metabolic syndrome, and cancer risk. |
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| Identify the appropriate patient populations for MASLD screening and utilize non-invasive tests like the FIB-4 index to risk-stratify patients for advanced fibrosis. |
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| Explain the foundational role of lifestyle modifications, specifically the degree of weight loss required to improve steatosis, inflammation, and fibrosis. |
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| Compare the mechanisms of action, indications, and clinical benefits of newly approved pharmacotherapies for MASH, including resmetirom and semaglutide. |
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| Discuss the emerging therapeutic landscape for MASH and the potential role of next-generation agents in managing the disease. |
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