| Describe the context and need for advanced training in medical management of CBRN casualties. |
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| Apply the CRESS algorithm to identify toxidromes (consciousness, respirations, eyes, secretions, skin). |
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| Identify opportunities to treat chemical, biological, radiological, and nuclear (CBRN) casualties through the LADMER (liberation, absorption, distribution, metabolism, elimination, response) approach. |
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| Recognize useful reference materials for management of CBRN casualties. |
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| Describe nerve agent pathophysiology from molecular to patient level. |
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| Manage nerve agent casualties at the Role 3/4, and intensive care setting. |
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| Recognize novel and contingency treatments for cholinergic crisis. |
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| Integrate NATO-Ally formularies to manage nerve agent casualties. |
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| Prepare for management of multiple simultaneous severe nerve agent casualties. |
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| Describe fundamental principles for identifying and treating a casualty with a metabolic agent intoxication. |
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| Describe the pharmacokinetic properties of naloxone, including its absorption, distribution, metabolism, and elimination. |
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| Identify an appropriate antidote for a person poisoned with thallium or arsenic describing its mechanism of action and administration protocol. |
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| Select the appropriate pharmacological agent to manage agitation, autonomic activity, and prevent or treat seizures, given a case involving a patient exposed to anticholinergic agents. |
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| Describe the importance of and initial formation of the Department of Defense (DoD) and Food and Drug Administration’s (FDA’s) Shelf-Life Extension Program (SLEP). |
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| Summarize eligibility requirements for enrolling medications into SLEP. |
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| Outline chemical treatment considerations for chemical and nerve agent exposures. |
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| Identify inventory considerations and potential use rates when responding to a chemical attack. |
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| Compare USCENTCOM’s informal SLEP program to the DoD’s SLEP program. |
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| Identify the clinical effects and rates of recovery of pulmonary agents and vesicants. |
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| Summarize the pharmacological therapies used to manage patients exposed to pulmonary agents and vesicants. |
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| Given a patient case, select the agent used and appropriate treatment based on exposure history and symptoms. |
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